Best Joint Supplements 2022: Top 5 Joint Health Products

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Updated on - Written by
Medically reviewed by Kimberly Langdon, MD

Relief Factor-1

Relief Factor

  • Unique combination of botanicals with fish oil

Organifi Move-1

Organifi Move

  • Nourishes joints and lowers systemic inflammation

1MD Move MD-1

1MD Move MD

  • Excellent joint nutrition and joint protection

Joint pain is the leading cause of disability globally. There could be many reasons for joint pains. Among them, the most common cause is osteoarthritis affecting mainly larger joints like the knee and hip joints. Another painful condition that is pretty common is low back pain.

Studies show that about 10% of men and 13% of women[1] above the age of 60 are living with osteoarthritis. Similarly, the prevalence of low back pain is about 7-8%[2].

Painful joint conditions tend to be chronic. Though they progress slowly, they continue to cause significant pain and inflammation. Even if medications can control pain in these conditions, these painful joint disorders tend to reoccur.

Doctors would often prescribe non-steroidal anti-inflammatory drugs and other medications when it comes to treatment options. However, these medications have numerous side effects.

Thus, those living with joint disorders often use natural joint supplements. These supplements are safe and good for prolonged use. They may help reduce the severity of the pain and inflammation and prevent disease progression. However, choosing the right kind of supplement may be challenging due to the sheer choice.

5 Supplements For Joint Pain 2022

Feature of Joint Supplements

A good joint supplement can suppress both pain and inflammation. Additionally, such a supplement must help manage underlying health issues. Further, any such supplement must be safe for older adults, as most joint pains occur in an aging population.

The Line Up At A Glance

Relief Factor-1

Editor’s choice

Relief Factor

  • Fish oil content means that it is not just good for joints but also for the heart and the brain
  • Excellent inflammation-reducing properties due to its content of fish oil, antioxidant, and curcumin.
  • Among the few joint supplements that promote blood flow due by boosting NO production

1MD Move MD-1

Most Potency

1MD Move MD

  • Dual-mode of action that is anti-inflammatory and joint nourishment
  • Fast-acting with relief in 5 days
  • Boost production of connective tissues and reduces joint stiffness

Physio Flex Pro-1

Best Variety

Physio Flex Pro

  • Help improve the quality of synovial fluid
  • Reduces inflammation and prevents further cartilage degradation
  • Fast pain relief

Nuzena Joint Support

Joint health with antiaging

Nuzena Joint Support

  • Reduces inflammation and boosts immunity
  • Powerful antioxidants
  • Stimulates cartilage growth and thus a reversal of joint disorders

Organifi Move-1

Joint health with detoxification

Organifi Move

  • Contain many ingredients for joint health and wellbeing
  • Good for boosting immunity
  • Good option for those living with liver problems, too

Top 5 Best Joint Supplements 2022

Relief Factor

Relief Factor-1

This joint supplement differs significantly from other supplements with quite a high content of antioxidants and powerful anti-inflammatory action. Additionally, most of its components are also good for metabolic health and have anti-aging properties.

  • Completely made of natural supplements
  • Fish oil content means that it is not just good for joints but also for the heart and the brain
  • Excellent inflammation-reducing properties due to its content of fish oil, antioxidant, and curcumin
  • Among the few joint supplements that promote blood flow due by boosting NO production
  • Does not contain vitamins or nutrients beneficial for joint health

It is an excellent antioxidant due to its content of resveratrol, turmeric, and omega-3 fatty acids. This may help prevent further damage to the joints, and at the same time, it may also help reduce the risk of various other chronic ailments like heart disorders and brain health issues.

Its components are also good for those living with metabolic disorders. Thus, resveratrol and omega-3 are quite good for improving cardiovascular health. In addition, these components have a positive impact on the blood lipid profile.

Many people use curcumin for joint disorders to suppress inflammation and reduce pain. However, this supplement also has other well-proven anti-inflammatory components like omega-3 fatty acids and resveratrol.

Lastly, but most importantly, what sets this supplement apart is its content of icariin. This natural compound is known to improve gene expression and the production of various enzymes that help prevent joint destruction and reduce inflammation. Additionally, it is a potent NO booster and thus good for cardiovascular health, and it even boosts male sexual health.

Move MD

1MD Move MD-1

An excellent joint supplement that is good for reducing inflammation. However, this supplement is even better for boosting regenerative processes. Despite the claimed immediate effect, it is rather good in the long term due to its ability to improve connective tissue production.

  • Dual-mode of action that is anti-inflammatory and joint nourishment
  • Fast-acting with relief in 5 days
  • Boost production of connective tissues and reduces joint stiffness
  • Antioxidants with much broader health benefits
  • Good for reducing inflammation, though it may need greater time for pain relief
  • Some people might be allergic to collagen protein

When it comes to joint pain, it mainly occurs for two reasons: inflammation and continued degenerative processes. Thus, an ideal joint supplement must try to handle both these issues.

This supplement contains components like Boswellia serrata and astaxanthin, which are quite good for reducing inflammation. Additionally, both these components are powerful antioxidants and help neutralize free radicals. It means that the supplement can help arrest further joint damage.

Controlling inflammation is good, but it is essential to provide the body with nutrients that can promote tissue regeneration for long-term joint pain relief. This supplement contains two powerful and proven nutrients known to boost the production of connective tissues. These are collagen protein and hyaluronic acid.

Hyaluronic acid is also good in the way that it improves the viscosity of the synovial fluid. Thus, this supplement may be particularly good for those living with the painful condition of larger joints like knee joints.

Physio Flex Pro

Physio Flex Pro-1

This joint supplement is good in the way that it contains mostly ingredients that are well-proven to work, like glucosamine, chondroitin, or curcumin. Thus, the product may have more reliable and predictable results.

  • Help improve the quality of synovial fluid
  • Reduces inflammation and prevents further cartilage degradation
  • Fast pain relief
  • Promotes regenerative processes and thus may even reverse some disease-related issues
  • Relatively more expensive

This product is good for faster pain relief due to its sufficient content of curcumin. But that is not all. And it has a high potency and is highly bioavailable for curcuminoids. Additionally, the supplement contains piperine, which is an excellent bioavailability enhancer, especially for turmeric.

It also contains selenium, one of the important micronutrients that is difficult to get via diet. It can help reduce inflammation and has an immunomodulatory effect. Selenium can be especially good for those living with low immunity and may even help protect them from certain infectious diseases.

The next good thing about this supplement is its content of joint nourishing natural ingredients like MSM., Chondroitin, and glucosamine. There are very few supplements that have all these three well-proven building blocks of the joints. These components are especially good for reversing joint problems in the long run.

This supplement is a kind of no-risk supplement, as it contains ingredients well-proven by science. However, it also contains highly bioavailable ingredients, which may explain why this supplement is so good.

The supplement contains glucosamine derived from shellfish, and thus it is of natural origin. However, this also means that those allergic to shellfish may need to avoid the supplement.

Nuzena Joint Support

Nuzena Joint Support

It is a perfect balance of the right kind of ingredient in the right amount. Thus, there is a well-proven ingredient like glucosamine and chondroitin. However, it is also good for modulating the disease process due to its high anti-inflammatory and antioxidant compounds content.

  • Good for both men and women
  • Reduces inflammation and boosts immunity
  • Powerful antioxidants
  • Stimulates cartilage growth and thus a reversal of joint disorders
  • Helps reduce morning stiffness
  • It may need a longer time for pain reduction.

Glucosamine is among the most well-proven natural ingredients for joint pain. It works in at least two known ways. First, it reduces joint inflammation and also promotes cartilage regeneration. It has a nourishing effect and also alters immune responses.

Glucosamine works best when combined with chondroitin. Using these compounds at the right dosage is the most popular approach and is well proven by numerous clinical studies.

However, what sets this joint supplement apart from other glucosamine and chondroitin supplements is its high content of disease-modifying ingredients. It contains turmeric and bromelain; both are quite good for quick pain relief and reducing joint inflammation.

Similarly, Boswellia, which is an extract from a plant that grows mostly in sub-tropical regions of Asia and Africa, is quite good for reducing inflammation and providing relief to joint pain.

Additionally, it also contains one of the most potent antioxidants, quercetin. It not only helps prevent joint cartilage but has numerous health benefits. Quercetin is quite good for metabolic health and can help reduce blood sugar. It is also good for cardiovascular health. Some studies suggest that it may help prevent certain cancers, too.

Organifi Move

Organifi Move-1

A unique approach as the supplement not only focuses on joint health but also on wellbeing. It is not merely a joint supplement but contains many superfoods and is thus good for immunity and liver health.

  • Contain many ingredients for joint health and wellbeing
  • Good for boosting immunity
  • A good option for those living with liver problems, too
  • It may need a longer time to start acting

This supplement is not just a joint supplement but also rich in superfoods that can help in a range of health conditions. Thus, it contains turmeric and astaxanthin, which are proven almost beyond any doubt for their benefits in joint health. These natural components help reduce pain and inflammation and prevent further joint damage.

The product also contains pine bark extract, which is a potent antioxidant, antimicrobial, and anti-inflammatory agent. It is not just good for joints but is one of the excellent anti-aging natural extracts. In addition, it promotes wound healing, prevents bone loss, prevents brain disorders, and is also good for male sexual health.

It also contains holy basil, which is excellent at boosting immunity and preventing seasonal ailments. It can also reduce disease-related stress and anxiety.

Similarly, milk thistle in the supplement is one of the best-known natural remedies for liver health and detoxification.

What Is a Joint Supplement?

Joint supplements are poly-component natural supplements that have anti-inflammatory and antioxidant properties. Additionally, they have ingredients that can nourish joint cartilage and improve synovial fluid production. Most joint supplements reduce pain and morning stiffness, too.

Which Joint Supplements Have Proven Benefits?

Many ingredients are quite good for joint health. For example, glucosamine and chondroitin nourish joints and reduce inflammation. Similarly, turmeric can be quite good for reducing pain and inflammation, with effects comparable to many commonly used drugs. All above supplements have these components, and thus they have proven benefits.

Tips For Choosing a Supplement

When choosing joint supplements, look for a few things, like all ingredients must be natural. Instead, any good supplements must-have ingredients that help in multiple ways, thus helping to reduce pain, and inflammation, protect cartilage and nourish joints.

Final Thought

Above are some of the best joint supplements available in 2022. They have ingredients proven to work by science. However, though there are many joint supplements, not all are equally good. Additionally, choosing the right joint supplement is quite a challenge due to the sheer number of offers. Thus, here we have simplified the task of selecting the right supplement by providing the pros and cons along with details of the best joint supplements.

Frequently Asked Questions

What are the main causes of joint pain?

Osteoarthritis is the leading cause of joint pain. It is more common in older adults. Additionally, obese individuals or those living with metabolic disorders are at a greater risk of joint pain.

Is it safe to use these joint supplements with prescription medications?

Doctors generally prescribe medications like non-steroidal anti-inflammatory drugs for pain. All these supplements are quite safe to use along with painkillers.

Can these supplements revere joint disorder?

Joint disorders mainly occur due to age-related wear and tear, and thus they are quite challenging to reverse. Thus, these joint supplements are more likely to provide pain relief and prevent disease progression.

 Are these products US FDA approved?

US FDA does not approve health supplements. However, it does inspect the manufacturing facilities and check supplements for their safety. Therefore, these products are produced using the highest standards as recommended by the US FDA.

Can these health supplements cause side effects?

Though these are some of the safest supplements on the market, any health supplement may cause some side effects. Fortunately, most side effects are short-lived and transient.


+ 5 sources

Tnhealth has strict sourcing guidelines and relies on peer-reviewed studies, academic research institutions, and medical associations. We work mostly with peer-reviewed studies to ensure accurate information. We avoid using tertiary references. You can learn more about how we ensure our content is accurate and current by reading our editorial policy.

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  2. Wu, A., March, L., Zheng, X., Huang, J., Wang, X., Zhao, J., Blyth, F.M., Smith, E., Buchbinder, R. and Hoy, D. (2020). Global low back pain prevalence and years lived with disability from 1990 to 2017: estimates from the Global Burden of Disease Study 2017. Annals of Translational Medicine, [online] 8(6), pp.299–299. doi:10.21037/atm.2020.02.175.
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Written by:

Rick Bayer, MD

Medically reviewed by:

Rick is a Final Year Medical Student. Passionate about medicine, fitness and personal growth, he is always ready to challenge himself to accomplish tasks and especially spread correct medical information to people. Rick is a long-term medical writer for several sites. With more than 5 years of experience in medical writing, he has completed 200+ projects with private and business clients.

Medically reviewed by: