10 Best Fish Oil Supplements: The Most Favored Options in 2022

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Medically reviewed by Drew Sutton

Life Extension Super Omega-3

Life Extension Super Omega-3

  • Third-party tested
  • Gluten-free
  • High EPA content in each serving

HUM Nutrition OMG! OMEGA the Great

HUM Nutrition OMG! OMEGA the Great

  • Gluten-free
  • Third-party tested
  • No artificial additives

Barlean’s Ideal Omega3 Softgels

Barlean’s Ideal Omega3 Softgels

  • One-a-day design
  • Third-party tested
  • Comes in a tasty orange flavor

Fish oil supplementation contains significant omega-3 fatty acids, which offer a vast range of health benefits. These polyunsaturated[1] fats can boost brain functionality and cardiovascular health and promote the immune system. Omega 3s are categorized into three groups:

  • ALA (alpha-linolenic acid)
  • DHA (docosahexaenoic acid)
  • EPA (eicosapentaenoic acid)

Fish oils are a convenient, fast, and reliable way of nourishing the body with omega-3, especially if you do not eat fish regularly. DHA and EPA are naturally active types of omega-3 fatty acids[2] and are primarily obtained from fish. ALA is plant-based; therefore, the body needs to convert it before it’s utilized.

Taking fish oil supplementation nourishes the body with a vast range of health benefits. Omega-3s contain anti-inflammatory properties and therefore alleviates chronic inflammation, especially heart disease. DHA and EPA are beneficial in reducing the risk of cardiovascular ailments since they can reduce high levels of triglyceride[3]. Also, omega-3 fatty acids are vital in eye development and can be beneficial in dry eye disease[4].  They are essential for brain health. During childhood and infancy, omega-3s are vital for neurological development[5]. For adults, omega-3 products[6] can prevent mental decline and stroke.

This article lists some of the best and most reputable brands that provide top-tier quality fish oil products. These are among the most reputable dietary supplements and uphold ultimate transparency. We considered various vital factors when choosing the best brands, including pricing, fish oil source, quality, and third-party testing. The products listed here are manufactured under GMP and FDA-certified facilities. Let us dive in, shall we?

10 Best Fish Oil Supplements: The Most Favored Options in 2022

What Is Fish Oil Supplement?

This is a dietary product that contains high levels of omega-3 fatty acids. The body needs omega 3s for cell growth, muscle function, and much more. These fatty acids can be obtained from fatty fish such as trout, mackerel, and salmon. They can also be obtained from vegetables, seeds, and nuts. These supplements come in pill, liquid, or capsule form and contain anti-inflammatory properties. They have various health benefits, such as alleviating the following health conditions:

  • Heart disease
  • High cholesterol and triglycerides
  • High blood pressure
  • Rheumatoid arthritis

How To Choose Fish Oil Supplement For Every Age

The following are various factors to consider when choosing to fish oil dietary products:

  • Fish oil source
  • Product Quality
  • Dosage[7]
  • Type of supplement, i.e., liquid, gummies, pills, or capsules forms

The Line Up At A Glance

Life Extension Super Omega-3

Best overal

Life Extension Super Omega-3

  • Third-party tested
  • Gluten-free
  • High EPA content in each serving

HUM Nutrition OMG! OMEGA the Great

Best fish oil subscriptions

HUM Nutrition OMG! OMEGA the Great

  • Gluten-free
  • Third-party tested
  • No artificial additives

Barlean’s Ideal Omega3 Softgels

Best-tasting

Barlean’s Ideal Omega3 Softgels

  • One-a-day design
  • Third-party tested
  • Comes in a tasty orange flavor

Nordic Naturals Ultimate Omega

Best potency

Nordic Naturals Ultimate Omega

  • Third-party tested
  • Minimal and high-potency ingredients
  • Lemon flavor

Carlson Labs, The Very Finest Fish Oil

Best liquid type

Carlson Labs, The Very Finest Fish Oil

  • Minimal ingredients
  • Non-GMO certified
  • Third-party tested

Amazon Elements Super Omega3

Best affordable

Amazon Elements Super Omega3

  • Affordable
  • Non-GMO
  • Gluten-free

Care/of Fish Oil Wild at Heart

Best for subscriptions

Care/of Fish Oil Wild at Heart

  • Non- GMO
  • Gluten-free
  • Third-party tested

Thorne Omega-3 with CoQ10

Best for heart health

Thorne Omega-3 with CoQ10

  • Gluten-free
  • Third-party tested
  • Contains coenzyme Q10

Nature Made Fish Oil

Best value

Nature Made Fish Oil

  • Third-party tested
  • Affordably priced
  • Gluten-free

Innovix Labs Triple Strength Omega-3

Best softgel

Innovix Labs Triple Strength Omega-3

  • Third-party tested
  • One-a-day design
  • Enteric-coated

10 Most Favored Fish Oil Supplements For 2022

Life Extension Super Omega-3

Life Extension Super Omega-3

These are among the best fish oil dietary supplements. They contain combined EPA and DHA of 1200 mg per serving.

  • Third-party tested
  • Gluten-free
  • High EPA content in each serving
  • Non-GMO certified
  • Some reviews indicate it comes with a fishy smell

Life extension is an excellent option to prevent the risk of cardiovascular disease. It has antioxidant properties since it contains high olive extract content. This ingredient boosts heart health. This supplement also features sesame seed lignans[8] which contain antioxidant and antimicrobial agents that preserve the oil. The oil is obtained from sustainably sourced anchovies on Chile’s coast. It also comes in two varieties, including easy-to-swallow and enteric-coated softgels. It is also approved by the IFOS[9](International Fish Oil Standards). IFOS is a highly reputable organization that assesses the strength and potency of fish oil supplementation.

HUM Nutrition OMG! OMEGA the Great

HUM Nutrition OMG! OMEGA the Great

This supplement is an ideal option for anyone who enjoys the reliability and convenience of subscription services. Each piece contains 1400 mg of combined EPA and DHA per serving.

  • Gluten-free
  • Third-party tested
  • No artificial additives
  • Sourced from wild-captured anchovies
  • Huge capsule
  • Pricey
  • Not ideal for pescatarians

This company offers subscription services for all dietary supplements. The supplement contains 1400 mg of combined EPA and DHA content per serving. The brand prioritizes safety; therefore, all products undergo rigorous third-party testing to guarantee safety, purity, and potency. The supplements do not contain any artificial colors, sweeteners, or additives and are gluten- and GMO-free. Signing up for a subscription makes these products less pricey.

Barlean’s Ideal Omega3 Softgels

Barlean’s Ideal Omega3 Softgels

This product contains 250 mg and 750 mg of DHA and EPA per serving. Each container has sixty pieces and is an excellent option for anyone not wishing to experience a fishy aftertaste of many fish oil dietary products.

  • One-a-day design
  • Third-party tested
  • Comes in a tasty orange flavor
  • Uses sustainable fishing practices
  • Pricey

This supplement is an excellent option for anyone who wishes to enjoy fish oil without the fishy smell and taste. The product is five-star rated by the IFOS, boosting its premium quality products. Also, it is approved by the Marine Stewardship Council[10] (MSC) since it focuses on applying sustainable fishing practices.

Nordic Naturals Ultimate Omega

Nordic Naturals Ultimate Omega

These softgels are among the best dietary supplements on the market. They contain 650 mg of EPA and 450 mg of DHA per serving.

  • Third-party tested
  • Minimal and high-potency ingredients
  • Lemon flavor
  • Certified sustainable
  • Non-GMO
  • Pricey

These fish oil softgels are an excellent option for adults. It has a combination of 1100 grams of DHA and EPA per serving. These soft gels are approved by Friend of the Sea, a company that makes sure seafood is obtained from sustainable aquaculture and fisheries. The brand sources raw materials from wild-caught anchovies and sardines. These soft gel capsules do not have a fish-like aftertaste since they come in a tasty lemon flavor. The brand has COA for all products to guarantee potency, efficacy, and freedom from heavy metals.

Carlson Labs The Very Finest Fish Oil

Carlson Labs, The Very Finest Fish Oil

This fish oil dietary product comes in a liquid form. Each container can offer up to a hundred servings.

  • Minimal ingredients
  • Non-GMO certified
  • Third-party tested
  • Comes in orange and lemon flavors
  • Liquid fish oil
  • Some users report a leaky cap

If you do not like swallowing capsules of softgels, this liquid fish oil supplement is an excellent option. Sourced from wild-caught mackerel, sardines, and anchovies. It is approved by the IFOS and undergoes third-party testing to guarantee potency, safety, and efficacy. The supplement is certified as Non-GMO and gluten-free. It also contains vitamin E[11], a fat-soluble vitamin with antioxidant properties. This product also comes in orange and lemon flavors; therefore can be enjoyed with juices or smoothies.

Amazon Elements Super Omega-3 with Lemon Flavor

Amazon Elements Super Omega3

This fish oil supplement contains an 1100 potency from EPA and DHA per serving. Also, this is an excellent product if you are operating on a tight budget but need quality fish oil.

  • Affordable
  • Non-GMO
  • Gluten-free
  • Sourced from wild-caught small fish
  • Batch tested
  • Not Third-party tested

This company sources fish oil from small fish such as mackerel, sardines, and anchovies. It does not contain artificial flavors, colors, or additives and is GMO- and gluten-free. Each batch is tested to ensure all ingredients are within the legal levels. These supplements are manufactured under FDA and GMP-standard facilities. The brand provides a COA for every batch.

Care/of Fish Oil Wild at Heart

Care/of Fish Oil Wild at Heart

These soft gels contain 220 mg of DHA and 180 mg of EPA per serving. This supplement is ideal for anyone looking for a lower dosage and subscription service convenience.

  • Non- GMO
  • Gluten-free
  • Third-party tested
  • Uses wild-caught salmon from Alaska
  • Batch tested
  • Pricey
  • Not ideal for pescatarians

These soft gels can be automatically delivered to you on a monthly basis. They contain sustainably sourced salmon oil from Alaska. The brand obtains salmon oil through a high-tech, cold press extraction to design stellar quality products. Also, the products contain water, mixed tocopherols, glycerine, and bovine-obtained gelatin. The brand prioritizes safety; therefore, these supplements undergo third-party testing to guarantee potency, purity, and safety.

Thorne Omega-3 with CoQ10

Thorne Omega-3 with CoQ10

This fish oil supplementation contains a combined EPA and DHA 630 mg per serving. It is an excellent option for anyone seeking to consume a CoQ10 dietary supplement.

  • Gluten-free
  • Third-party tested
  • Contains coenzyme Q10
  • Pricey

This product contains CoQ10[12], which has antioxidant properties. This makes this high-quality fish oil supplement beneficial for the heart and boosts energy levels in the cells. The product contains 630 mg of combined DHA and EPA, and 30 mg of CoQ10, per serving. The brand prioritizes safety; therefore, all supplements undergo rigorous third-party testing to guarantee efficacy, quality, and purity.

Nature Made Fish Oil Plus Vitamin D 1,000 IU

Nature Made Fish Oil

This is one of the most affordable fish oil products. It undergoes third-party laboratory testing and contains additional vitamin D.

  • Third-party tested
  • Affordably priced
  • Gluten-free
  • Obtained from wild-caught small fish
  • Does not disclose the exact EPA and DHA content

Nature Made is one of the market’s most affordable fish oil supplements. It contains additional D vitamins[13] that are rare in many food sources. These products are obtained from wild-caught fish and are meticulously purified to remove harmful compounds such as mercury, PCBs, furans, and dioxins. Also, these products are approved by the USP (U.S Pharmacopeia). USP[14] is an NGO that sets high standards for purity, potency, quality, and packaging for supplements.

Innovix Labs Triple Strength Omega-3

Innovix Labs Triple Strength Omega-3

This supplement is a one-a-day formulation and is obtained from wild-captured small fish.

  • Third-party tested
  • One-a-day design
  • Enteric-coated
  • Obtained from wild-captured small fish
  • Big capsule size

This supplement is five-star rated by the IFOS. It also used sustainably sourced small fish such as mackerel, sardines, and anchovies. These small fish undergo rigorous purification to ensure they are free from harmful compounds such as mercury. These capsules are meticulously enteric coated to ensure they do not break before reaching the stomach. This also prevents fish burps and aftertaste.

Who Might/Might Not Benefit From Fish Oil Supplements?

The following are various health conditions that these supplements can alleviate:

  • Involuntary weight loss
  • Angioplasty
  • Menstrual cramps
  • Kidney damage
  • Heart failure
  • Vomiting and nausea
  • High cholesterol levels
  • High blood pressure
  • Nephropathy
  • Fatty liver disease
  • Joint pain from rheumatoid arthritis

The following are various health conditions where these supplements might not be effective:

  • AMD (Age-related macular degeneration
  • Atherosclerosis
  • Chest pain
  • Atrial fibrillation
  • Eczema
  • Bronchopulmonary
  • Bipolar disorder
  • Cognitive function
  • Cerebrovascular ailments
  • Bronchopulmonary
  • Breast pain
  • And many more

How To Use Fish Oil Supplements Effectively

Studies show that prominent benefits from fish oil dietary products are not immediate; rather, they are long-term[15]. When using these supplements, timing is important. You can adjust the supplementation’s timing to prevent common side effects such as acid reflux. Splitting the oil into manageable doses and consuming it in the evening and evening is an excellent strategy that can reduce indigestion and acid reflux[16]. Having a meal enhances absorption. Also, taking fish oil supplements should not be done on an empty stomach. For prominent long-term results, follow the manufacturer’s instructions consistently.

Frequently Asked Questions

Are there any side effects?

Some users report nausea, belching, and diarrhea.

Does the FDA approve?

The FDA does not approve of any dietary supplement.

What is the most effective fish oil product?

The ones described above are among the top-selling and most reputable brands.

Are they safe?

These products are generally safe; however, always be keen when purchasing. Check the brand’s reputation.

Is there an age limit?

These supplements are designed for consumption by people of all ages.

What should I consider when buying?

Source of fish oil, quality of product, third-party lab testing, pricing, type of product, customer reviews, and many more.

What are the health benefits?

These supplements can boost our health in various ways, including preventing heart-related problems regulating cholesterol and blood pressure, and much more.

Who should avoid these supplements?

Suppose you are using warfarin or other blood thinners. These products might react with these drugs and increase the probability of bleeding.


+ 16 sources

Tnhealth has strict sourcing guidelines and relies on peer-reviewed studies, academic research institutions, and medical associations. We work mostly with peer-reviewed studies to ensure accurate information. We avoid using tertiary references. You can learn more about how we ensure our content is accurate and current by reading our editorial policy.

  1. Nih.gov. (2015). Office of Dietary Supplements – Omega-3 Fatty Acids. [online] Available at: https://ods.od.nih.gov/factsheets/Omega3FattyAcids-HealthProfessional/ [Accessed 29 Oct. 2022].
  2. Nih.gov. (2022). Office of Dietary Supplements – Omega-3 Fatty Acids. [online] Available at: https://ods.od.nih.gov/factsheets/Omega3FattyAcids-Consumer/#:~:text=The%20three%20main%20omega%2D3,in%20fish%20and%20other%20seafood. [Accessed 29 Oct. 2022].
  3. Nih.gov. (2015). Office of Dietary Supplements – Omega-3 Fatty Acids. [online] Available at: https://ods.od.nih.gov/factsheets/Omega3FattyAcids-HealthProfessional/ [Accessed 29 Oct. 2022].
  4. Downie, L.E., Ng, S.M., Lindsley, K.B. and Akpek, E.K. (2019). Omega-3 and omega-6 polyunsaturated fatty acids for dry eye disease. Cochrane Database of Systematic Reviews. [online] doi:10.1002/14651858.cd011016.pub2.
  5. Nih.gov. (2015). Office of Dietary Supplements – Omega-3 Fatty Acids. [online] Available at: https://ods.od.nih.gov/factsheets/Omega3FattyAcids-HealthProfessional/ [Accessed 29 Oct. 2022].
  6. Román, G.C., Jackson, R.E., Gadhia, R., Román, A.N. and Reis, J. (2019). Mediterranean diet: The role of long-chain ω-3 fatty acids in fish; polyphenols in fruits, vegetables, cereals, coffee, tea, cacao and wine; probiotics and vitamins in prevention of stroke, age-related cognitive decline, and Alzheimer disease. Revue Neurologique, [online] 175(10), pp.724–741. doi:10.1016/j.neurol.2019.08.005.
  7. Nih.gov. (2022). Office of Dietary Supplements – Omega-3 Fatty Acids. [online] Available at: https://ods.od.nih.gov/factsheets/Omega3FattyAcids-Consumer/#:~:text=The%20three%20main%20omega%2D3,in%20fish%20and%20other%20seafood. [Accessed 29 Oct. 2022].
  8. Romani, A., Ieri, F., Urciuoli, S., Noce, A., Marrone, G., Nediani, C. and Bernini, R. (2019). Health Effects of Phenolic Compounds Found in Extra-Virgin Olive Oil, By-Products, and Leaf of Olea europaea L. Nutrients, [online] 11(8), p.1776. doi:10.3390/nu11081776.
  9. Certifications by Nutrasource. (2022). IFOS. [online] Available at: https://certifications.nutrasource.ca/about/how-certifications-work/ifos [Accessed 29 Oct. 2022].
  10. US & Canada – English. (2022). Home. [online] Available at: https://www.msc.org/en-us [Accessed 29 Oct. 2022].
  11. Nih.gov. (2021). Office of Dietary Supplements – Vitamin E. [online] Available at: https://ods.od.nih.gov/factsheets/VitaminE-Consumer/ [Accessed 29 Oct. 2022].
  12. Sood, B. and Keenaghan, M. (2022). Coenzyme Q10. [online] Nih.gov. Available at: https://www.ncbi.nlm.nih.gov/books/NBK531491/ [Accessed 29 Oct. 2022].
  13. Nih.gov. (2022). Office of Dietary Supplements – Vitamin D. [online] Available at: https://ods.od.nih.gov/factsheets/VitaminD-Consumer/ [Accessed 29 Oct. 2022].
  14. Usp.org. (2022). US Pharmacopeia (USP). [online] Available at: https://www.usp.org/ [Accessed 29 Oct. 2022].
  15. NCCIH. (2018). Omega-3 Supplements: In Depth. [online] Available at: https://nccih.nih.gov/health/omega3/introduction.htm.
  16. Cleland, L., James, M. and Proudman, S. (2006). Arthritis Research & Therapy, [online] 8(1), p.202. doi:10.1186/ar1876.

Written by:

Rick Bayer, MD

Medically reviewed by:

Rick is a Final Year Medical Student. Passionate about medicine, fitness and personal growth, he is always ready to challenge himself to accomplish tasks and especially spread correct medical information to people. Rick is a long-term medical writer for several sites. With more than 5 years of experience in medical writing, he has completed 200+ projects with private and business clients.

Medically reviewed by: